nos-trum. pronunciation: \nos'-trum\. noun. Etymology: Latin, neuter of noster our, ours.
1. a medicine of secret composition recommended by its preparer but usually without scientific proof of its effectiveness.
2. a usually questionable remedy or scheme.
See here for more discussion.

Wednesday, June 2, 2010

No Advantage To Spreading Out Or Delaying Vaccinations In Infants

Evidence against one of the Vaccine Myths that giving immunizations concurrently and on-time somehow causes neuropsychological damage.

During my military service, we would run across this urban myth from time to time.  Military recruits commonly receive a number of immunizations upon enlistment and commissioning.  There are standard restrictions against giving live virus vaccine at the same time as others, but these are all well-defined and the live virus-containing preparations are delayed (ex: yellow fever).  There's never been any evidence that giving the standard immunizations in multiples is harmful.  Unpleasant, yes, but not harmful.

Children are another story.  There are naturally greater concerns about giving vaccinations in infancy when the central nervous system is still developing rapidly.

This paper, appearing in "The Green Journal" as pediatricians call it (Pediatrics, doi:10.1542/peds.2009-2489) looked at 42 different neuropsychological parameters important in infant development and compared those children who received their immunizations as scheduled with those who had delayed or missed vaccinations.  None of the criteria were worse in the "on-time" group.  In fact, several of the neuropsych outcomes were improved.

For Onion Peelers, (statistics stuff)
Children were followed for 7-10 years.  "Timely vaccination was associated with better performance on 12 outcomes in univariate testing and remained associated with better performance for 2 outcomes in multivariable analyses. No statistically significant differences favored delayed receipt...children with the greatest vaccine exposure during the first 7 months of life performed better than children with the least vaccine exposure on 15 outcomes in univariate testing...No statistically significant differences favored the less vaccinated children."

Despite the fact that vaccination has been the second most effective public health measure in human history (the sanitation movement was number 1, antibiotics #3), there is an irrational fear that persists to this day.  I've written about this several times.  See here for starters.

This study deals another blow to the vaccine fear-mongers.

Doc D

No comments:

Post a Comment


What I'm Reading - Updated 3 May

Blog Archive